Publications

Authorship of original scientific and scholarly articles with major contributions in the fields of data science, genomics and data-driven discovery.

Identification of environmental factors that promote intestinal inflammation

Nature volume 611, pages 801–809 (2022)

data science | machine learning | genomics

Genome-wide association studies have identified risk loci linked to inflammatory bowel disease (IBD)1—a complex ch...

Whole-genome sequencing reveals host factors underlying critical COVID-19

Nature volume 607, pages 97–103 (2022)

causal inference | mendelian randomization | transcriptomics

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the dev...

The Role of the Disrupted Podosome Adaptor Protein (SH3PXD2B) in Frank–Ter Haar Syndrome

Genes (Basel). 2022 Feb; 13(2): 236. r

variant analysis | bioinformatics | computational biology

Frank–Ter Haar syndrome (FTHS), sometimes referred to as Ter Haar syndrome, is a rare hereditary disorder that man...

Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

Nature volume 590, pages 473–479 (2021)

Data-driven discovery | High-throughput flow cytometry

Astrocytes are glial cells that are abundant in the central nervous system (CNS) and that have important homeostat...

Role of sphingolipid metabolism in neurodegeneration

Journal of Neurochemistry volume 158, issue 1, pages 25-35

disease modeling | neuroinformatics | Therapeutic target identification

Sphingolipids are a class of lipids highly enriched in the central nervous system (CNS), which shows great diversi...